Disruption of female reproductive function by endotoxins
نویسندگان
چکیده
منابع مشابه
Endocrine disruption of oestrogen action and female reproductive tract cancers.
Endocrine disrupting chemicals (EDC) are ubiquitous and persistent compounds that have the capacity to interfere with normal endocrine homoeostasis. The female reproductive tract is exquisitely sensitive to the action of sex steroids, and oestrogens play a key role in normal reproductive function. Malignancies of the female reproductive tract are the fourth most common cancer in women, with end...
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Over the past two decades, it has become clear just how much of our physiology is under the control of the suprachiasmatic nucleus (SCN) and the cell-intrinsic molecular clock that ticks with a periodicity of approximately 24 h. The SCN prepares our digestive system for meals, our adrenal axis for the stress of waking up in the morning, and the genes expressed in our muscles when we prepare to ...
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We report here the toxic effects of chlorpyrifos, a broad-spectrum organophosphorous insecticide, on female reproductive function in rat model. We observed significant alterations in the rhythmicity and phasic cellular characteristics of estrous cycle with a concomitant increase in diestrus index in chlorpyrifos treated female rats in a dosedependent manner (5.4 and 8.1 mg/Kg.b.wt./day) compare...
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Mild-to-moderate alcohol use has numerous negative consequences for female reproductive function. Animal studies have shown that alcohol consumption disrupts female puberty, and drinking during this period also may affect growth and bone health. Beyond puberty, alcohol has been found to disrupt normal menstrual cycling in female humans and animals and to affect hormonal levels in postmenopausal...
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ژورنال
عنوان ژورنال: Reproduction
سال: 2018
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-17-0406